Ppv-4508235
PPV-4508235 was synthesized via a multi-step process involving the condensation of a piperazine scaffold with a proprietary heteroaryl moiety. The final product was purified to >99% HPLC purity.
The compound showed moderate plasma clearance and excellent brain penetration, with a brain-to-plasma ratio of 1.8 at 2 hours post-dosing. Oral bioavailability was calculated at 65% in rodents. ppv-4508235
If refers to a specific document ID (such as a court case, a patent document ID from a specific intellectual property office, or an internal corporate report), please provide additional context or the source database, and I can retrieve the specific information you are looking for. Oral bioavailability was calculated at 65% in rodents
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