The only official lossless source for Season 1 is the (released by Warner Bros. in 2014). Ripping the disc with MakeMKV yields a ~4–6 GB per episode remux, compared to ~400 MB streaming versions.
The episode starts with Rick inventing a potion that allows people to see and interact with alternate dimensions. However, Morty and Summer get exposed to the potion, causing chaos and destruction. rick and morty s01e02 lossless
The Rick Potion Season: 1 Episode: 2
Streaming services like Netflix, Hulu, and Max all apply compression (often lossy AAC or E-AC-3 audio, and re-encoded H.264/H.265 video). A “lossless” release typically means: The only official lossless source for Season 1